by GEMSOLIN CAPSULE
If you are known to be allergic to Gemsoline Softgel Capsule 15's or its inactive components, please inform your doctor. Please tell your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, and kidney stones before starting Gemsoline Softgel Capsule 15's. Pregnant or breastfeeding women should consult their doctor before taking Gemsoline Softgel Capsule 15's. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Gemsoline Softgel Capsule 15's may pass into the breast milk; hence breastfeeding mothers need to seek medical advice before starting Gemsoline Softgel Capsule 15's.
Use of gelling agents such as carrageenan and Gellan gum delays HPMC cell dissolution. Improved HPMC versions are available which do not require a secondary gelling agent (e.g., VCaps). HPMC dissolution and disintegration time is usually longer than that of hard gelatin capsules.
Gelling agents may interact with cations in dissociating medium such as potassium and calcium ions. However, dissolution of improved newer versions of HPMC capsules is independent of pH and the ionic nature of dissociating medium.
What happens if I miss a dose?If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Gemsoline-D3 60K Soft Gelatin Capsule 4's works by blocking liver enzymes, causing the liver to make less cholesterol. So, Gemsoline-D3 60K Soft Gelatin Capsule 4's increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Gemsoline-D3 60K Soft Gelatin Capsule 4's lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed.
Gemsoline-D3 60K Soft Gelatin Capsule 4's reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. Cholecalciferol is added to relieve the muscle pain caused due to atorvastatin. Collectively, Gemsoline-D3 60K Soft Gelatin Capsule 4's helps reduce cholesterol levels in the blood.
Regarding the vegetarian versus nonvegetarian issue, defining vegetarian is a difficult issue, with special reference to variation among different religious beliefs present. Many a times, manufacturing of drugs requires different reagents of animal origin. Again, different drug products are also of nonvegetarian origin, for example, hormonal products, heparin, insulin, antiserum, and human cell line-derived products. Involvement of all these complicated issues makes determination of vegetarian and nonvegetarian capsules complicated. Again, this will create chaos between patients and doctors regarding the prescription of vegetarian versus nonvegetarian capsules. Scientific and manufacturing advantages can guide in this issue. On the ethical basis, representation says that gelatin-based capsules should be allowed to be marketed without any additional labeling. “Some members also pointed out that HPMC – a type of cellulose capsules – is basically of synthetic origin and as such cannot be considered as purely of vegetarian origin as in the case of food preparations,” the minutes noted. The DTAB's decision is in line with the 2013 Supreme Court decision which stated that cosmetics and drugs cannot be treated at par with food articles, when it comes to labeling them with a brown or a green mark to distinguish the vegetarian and nonvegetarian ingredients and hence, we are with the decision of the Supreme Court.
Capsule, a form of dosage form in medication, are common in our day-to-day health management. Capsules are made up of gelatin (hard or soft) and nongelatin shells generally derived from hydrolysis of collagen (acid, alkaline, enzymatic, or thermal hydrolysis) from animal origin or cellulose based. However, currently, an issue of vegetarian and nonvegetarian capsules is coming up. The Central Drugs Standard Control Organization (CDSCO) has invited comments from different stakeholders regarding this.
FAQsExpand AllHow does Gemsoline Softgel Capsule 15's work?Gemsoline Softgel Capsule 15's is a dietary supplement that treats low levels of calcium in the blood. It consists of Calcium, Calcitriol, and Menaquinone. Calcium is a mineral and prevents or treats calcium deficiency.
Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the decreased activity of the parathyroid glands). Menaquinone (Vitamin K2) maintains bone density by promoting calcium transport from the bloodstream into the bone.What happens if I miss a dose?If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.Can I take Gemsoline Softgel Capsule 15's with milk?Milk is considered to be the best source of calcium. You can take Gemsoline Softgel Capsule 15's with milk.Does Gemsoline Softgel Capsule 15's cause kidney stones?Gemsoline Softgel Capsule 15's can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Gemsoline Softgel Capsule 15's as a daily supplement if you have any kidney problems or a history of kidney stones.Can I take Gemsoline Softgel Capsule 15's if I suffer from hypercalcemia (high levels of calcium in the blood)?Gemsoline Softgel Capsule 15's is used to increase low levels of calcium in the body. Hence it is not advised to use Gemsoline Softgel Capsule 15's during hypercalcemia, since it causes the overdose of calcium leading to kidney stones and other effects.Can I take Gemsoline Softgel Capsule 15's if I am undergoing dialysis?Calcitriol in Gemsoline Softgel Capsule 15's can increase inorganic phosphate levels in serum; hence it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low phosphate diet to control serum phosphorus levels in patients undergoing dialysis.
Manufacturing and priceGelatin capsules are being used worldwide for the past 100 years with known safety and toxicity profile. Gelatin is easily available from hydrolysis of collagen whereas manufacturing of HPMC is a synthetic process.
Raw materials for gelatin are readily available in the market which can fulfill the requirement of industries in India whereas raw materials for non-gelatin are quite less available and hence they are four times costlier than their gelatin counterpart. Moreover, most of the vegetable capsule shell technologies are in patent period, contributing to the cost component of these capsule shells.
The observations of Cole et al., 2004, describe that there is very little difference between HPMC capsules and conventional hard gelatin shells' in vivo and in vitro kinetic characteristics which is supported by Tuleu et al., 2007. Dissolution of both types of capsule shell was similar in water, whereas acidic environment (pH 1.2) and cations (K+/PO4 buffer) hinder HPMC capsule shell opening. Despite difference, there was no significant difference observed in terms of pharmacokinetic parameters such as Cmax and area under the curve. However, individuals fasted had lower mean disintegration time in case of gelatin capsules, compared to HPMC shells.
Both hard and soft capsule shells can be prepared from gelatin. Presence of 12%–16% moisture is essential for maintaining the integrity of gelatin hard capsule shell. Plasticizers, especially nonvolatile plasticizers, are used in the manufacturing of soft shells. These plasticizers reduce interaction between protein molecules and allow retention of moisture by gelatin. Glycerol and sorbitol are used commonly, but sorbitol is associated with blooming (crystallization), when stored at low humid temperature
. Hence, glycerol is blended with sorbitol. Polyethylene glycols (PEGs) can also be used.
A: Milk, curd, cheese, paneer and other dairy products, chinese cabbage, kale, broccoli and milk products. Zinc is found in beans, nuts, certain types of seafood (such as crab and lobster), whole grains, etc.
Will Gemsoline-D3 60K Soft Gelatin Capsule 4's reduce my fertility?There's no strong evidence to suggest that taking Gemsoline-D3 60K Soft Gelatin Capsule 4's will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if you're likely to get pregnant or pregnant.Is there any lifestyle help for reducing bad cholesterol in our blood?Increase your daily diet with fiber, fruits, vegetables, whole grains, and fish, and cut saturated fat as well. Stop smoking and drinking and try to work out every day as well.
Can I stop taking Gemsoline-D3 60K Soft Gelatin Capsule 4's without the doctor's advice?No, you should not stop taking Gemsoline-D3 60K Soft Gelatin Capsule 4's without consulting your doctor. Please take advice from the doctor before quitting.In which condition should I not take Gemsoline-D3 60K Soft Gelatin Capsule 4's?People affected with hypothyroidism (underactive thyroid), muscle weakness, joint pain, kidney disease, diabetes, liver disease, uncontrolled epilepsy, high or low potassium level, or severely low blood pressure.Can intake of Gemsoline-D3 60K Soft Gelatin Capsule 4's harm my baby in the pregnancy stage?There is no firm clinical evidence stating that an intake of Gemsoline-D3 60K Soft Gelatin Capsule 4's causes harm to the baby. However, Gemsoline-D3 60K Soft Gelatin Capsule 4's passes into the breast milk and may harm the baby.
It is advisable to consult a doctor if you are a nursing mother and taking Gemsoline-D3 60K Soft Gelatin Capsule 4's.Can Yoghurt lower cholesterol?Yogurt is a probiotic which can help in lowering the raised cholesterol level if taken with Gemsoline-D3 60K Soft Gelatin Capsule 4's. Yogurt eaters have a better metabolic profile than those who didn't eat yogurt.Are eggs bad for cholesterol?Egg yolks (yellow part of the egg) are high in cholesterol and rich in saturated fatty acids with a greater effect on our blood cholesterol levels. However, you can take a minimum of 3 whole eggs per day as eggs are considered a good source of HDL (good cholesterol).
If you have high cholesterol, please consult a doctor regarding intake of the yolk part of the egg.
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