PREDNISOLONE TABLET USE

PREDNISOLONE TABLET USE

People taking prednisone can also experience higher blood sugar, which is a special concern for those with diabetes. Because prednisone suppresses the body’s immune system, it can also increase the risk of infection. Therefore, some precautions need to be taken.



This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.

 Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).



This medication may cause bone problems (osteoporosis). Lifestyle changes that may help reduce the risk of bone problems while taking this drug for an extended time include doing weight-bearing exercise, getting enough calcium and vitamin D, stopping smoking, and limiting alcohol. 

Discuss with your doctor lifestyle changes that might benefit you.



What other information should I know? Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to prednisone.

If you are having any skin tests such as allergy tests or tuberculosis tests, tell the doctor or technician that you are taking prednisone.Do not let anyone else take your medication. 

Ask your pharmacist any questions you have about refilling your prescription.It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.

 You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Rifampicin induces the microsomal oxidation of glucocorticoids (hydrocortisone, prednisolone, methylprednisolone). This leads to an increased steroid need during rifampicin treatment and reduced steroid need after such treatment.

Precautions Before taking prednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. 

Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye disease (such as cataracts, glaucoma), heart problems (such as heart failure, recent heart attack), high blood pressure, liver disease, kidney disease, thyroid problems, diabetes, stomach/intestinal problems (such as diverticulitis, ulcer), brittle bones (osteoporosis), current/past infections (such as tuberculosis, positive tuberculosis test, herpes, fungal), bleeding problems, blood clots, mental/mood conditions (such as psychosis, anxiety, depression), low salts in the blood (such as low potassium or calcium), seizures.This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages. Consult your doctor or pharmacist for more information.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication.This medication may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.Tell your health care professional that you are using prednisolone before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).This medication may slow down a child's growth if used for a long time. Consult the doctor or pharmacist for more details. See the doctor regularly so your child's height and growth can be checked.

Older adults may be more sensitive to the effects of this drug, especially bone loss/pain, stomach/intestinal bleeding, and mental/mood changes (such as confusion).During pregnancy, prednisolone should be used only when clearly needed. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for an extended period of time may have hormone problems. Tell your doctor right away if you notice symptoms such as nausea/vomiting that doesn't stop, severe diarrhea, or weakness in your newborn.This medication passes into breast milk. However, this drug is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Prednisolone is a synthetic pregnane corticosteroid closely related to its cognate prednisone, having identical structure save for two fewer hydrogens near C11. It is also known as δ1-cortisol, δ1-hydrocortisone, 1,2-dehydrocortisol, or 1,2-dehydrohydrocortisone, as well as 11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione.[35][36]

Uses Prednisolone is a man-made form of a natural substance (corticosteroid hormone) made by the adrenal gland. It is used to treat conditions such as arthritis, blood problems, immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.

 How to use Prednisolone Tablet Take this medication by mouth, with food or milk to prevent stomach upset, exactly as directed by your doctor. Take this medication with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.Follow the dosing schedule carefully. The dosage and length of treatment are based on your medical condition and response to treatment. 

Your doctor may direct you to take prednisolone 1 to 4 times a day or take a single dose every other day. It may help to mark your calendar with reminders or use a pill box. If you are using the prednisolone dose pack, follow the dosing schedule on the package, unless directed otherwise by your doctor.Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.If you suddenly stop using this medication, you may have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness).

 To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used prednisolone for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal. See also Precautions section.Tell your doctor if your condition lasts or gets worse.

What is prednisone?Prednisone is a prescription steroid drug. It comes as an immediate-release tablet, a delayed-release tablet, and a liquid solution. You take all of these forms by mouth.Prednisone delayed-release tablet is available as a generic drug and as the brand-name drug Rayos. The immediate-release tablet is only available as a generic drug.Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.Why it’s usedPrednisone reduces inflammation in your body. It’s approved to treat:allergiesanemiaasthmabursitiscolitisdermatitisendocrine disorders such as adrenal insufficiency or congenital adrenal hyperplasiaeye inflammationeye ulcerlung diseases such as sarcoidosis or aspiration pneumonialupus and nephrotic syndromemultiple sclerosis exacerbationsoptic neuritisosteoarthritispsoriasisrheumatoid arthritisthrombocytopenia (low platelet count)symptoms of lymphoma or leukemiaHow it worksPrednisone works by weakening your immune system. This action blocks chemicals that normally cause inflammation as part of your body’s immune response, and can help decrease inflammation in many parts of your body.

Jika akan menggunakan prednisolone untuk hemoroid, sebaiknya lakukan setelah buang air besar. Oleskan obat pada hemoroid menggunakan tangan, kasa, atau aplikator yang tersedia pada kemasan obat.

Missed Dose If you are taking this medication once daily and miss a dose, take it as soon as you remember.

 If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. If you are taking this medication every other day, ask your doctor or pharmacist what you should do if you miss a dose.

Prednisolone is a man-made form of a natural substance (corticosteroid hormone) made by the adrenal gland.

 It is used to treat conditions such as arthritis, blood problems, immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.

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BETNISOLE OF USE

Betnisol TABLET USE

A steroid drug is the tablet form of betnesol. It is used to reduce associated symptoms in people with allergies, immune-related illnesses, rheumatoid arthritis, bronchial asthma, skin, and other allergic conditions.



What to do about:irritation, burning, stinging and itching in your eye – if you get these symptoms after putting in the eye drops, they should go after a few minutes as your eye gets used to the medicine. If they last longer and do not improve, stop using the eye drops or ointment and tell your doctor.blurred or cloudy vision – you may get some blurred or cloudy vision straight after putting the drops or ointment in your eye. If your sight does not go back to normal after a few minutes, or you think your sight is slowly getting worse, stop using the eye drops or ointment and tell your doctor.sneezing, blocked, irritated or dry nose, or nosebleeds – these will usually settle down as you get used to the medicine. Stop using your nose drops for a few days, then start again. Speak to your doctor if these side effects do not go away.

headaches and dizziness – try to rest and drink plenty of fluids. Do not drink too much alcohol. Talk to your doctor if the headache does not go away or is severe.changes in your sense of smell and taste a few minutes after your dose – rinse your mouth with water or have a drink of water.



Betnesol 0.5 MG Tablet is primarily prescribed to treat various rheumatic disorders such as systemic lupus erythematous and rheumatoid arthritis. It is also used against various skin diseases including psoriasis and dermatitis, allergic conditions such as angioedema and asthma, certain blood disorders, certain eye and skin conditions.

 Betnesol 0.5 MG Tablet belonging to the glucocorticoid class of medication, acts as a steroid. Multiple sclerosis, crohn's disease and leukaemia can also be treated with Betnesol 0.5 MG Tablet. Being a corticosteroid, it works by decreasing inflammation and modifying the body's immune response to various conditions. You are advised to not take this medication if you have allergy, systemic fungal infection or an active untreated infection. Betnesol 0.5 MG Tablet can interact with a few other medicines so inform your doctor if you take amlodipine, mifepristone, warfarin, ethinyl, estradiol, insulin, ciprofloxacin, BCG vaccine. Also inform your doctor if you suffer from tuberculosis, electrolytic imbalance, gastrointestinal perforations, infections, myocardial infarction, ocular herpes infection, scleroderma or threadworm infection. This medicine is not recommended to use during pregnancy or breastfeeding unless absolutely required, in which case breastfeeding should be discontinued. 

Serious side effects may include an increased risk of infection, severe allergic reactions, muscle weakness, and psychosis. Using Betnesol 0.5 MG Tablet for a long time can cause adrenal insufficiency. Discontinuing the medication suddenly after a long-term use may be dangerous.

 Take Betnesol 0.5 MG Tablet as instructed by the doctor. Your dosage duration, timings, forms and other attributes can vary depending on the medical condition and hence following instructions are necessary to ensure this medicine is safe and effective to use. Take oral medication with or after meals. Limit intake of caffeine or stimulants. Prescriber may recommend increased dietary vitamins, minerals, or iron. Diabetics should monitor glucose levels closely (antidiabetic medication may need to be adjusted). Inform prescriber if you are experiencing greater than normal levels of stress (medication may need adjustment). Some forms of this medication may cause GI upset (oral medication may be taken with meals to reduce GI upset; small frequent meals and frequent mouth care may reduce GI upset). You may be more susceptible to infection (avoid crowds and persons with contagious or infective conditions).



Getting ready to use your medicineCheck that the seal on the bottle is not broken before using Betnesol-N Drops for the first time. Wash and dry your hands. Do not breathe on or touch the dropper nozzle and do not touch the eyes, ear or nose with the dropper nozzle.If there is no improvement in your symptoms after 7 days, stop using the drops and see your doctor again.

About Betnesol 0.5 MG Tablet Betnesol 0.5 MG Tablet is primarily prescribed to treat various rheumatic disorders such as systemic lupus erythematous and rheumatoid arthritis. It is also used against various skin diseases including psoriasis and dermatitis, allergic conditions such as angioedema and asthma, certain blood disorders, certain eye and skin conditions. Betnesol 0.5 MG Tablet belonging to the glucocorticoid class of medication, acts as a steroid. Multiple sclerosis, crohn's disease and leukaemia can also be treated with Betnesol 0.5 MG Tablet. Being a corticosteroid, it works by decreasing inflammation and modifying the body's immune response to various conditions. You are advised to not take this medication if you have allergy, systemic fungal infection or an active untreated infection. Betnesol 0.5 MG Tablet can interact with a few other medicines so inform your doctor if you take amlodipine, mifepristone, warfarin, ethinyl, estradiol, insulin, ciprofloxacin, BCG vaccine. Also inform your doctor if you suffer from tuberculosis, electrolytic imbalance, gastrointestinal perforations, infections, myocardial infarction, ocular herpes infection, scleroderma or threadworm infection. This medicine is not recommended to use during pregnancy or breastfeeding unless absolutely required, in which case breastfeeding should be discontinued. Serious side effects may include an increased risk of infection, severe allergic reactions, muscle weakness, and psychosis. Using Betnesol 0.5 MG Tablet for a long time can cause adrenal insufficiency. Discontinuing the medication suddenly after a long-term use may be dangerous. Take Betnesol 0.5 MG Tablet as instructed by the doctor. Your dosage duration, timings, forms and other attributes can vary depending on the medical condition and hence following instructions are necessary to ensure this medicine is safe and effective to use. Take oral medication with or after meals. Limit intake of caffeine or stimulants. Prescriber may recommend increased dietary vitamins, minerals, or iron. Diabetics should monitor glucose levels closely (antidiabetic medication may need to be adjusted). Inform prescriber if you are experiencing greater than normal levels of stress (medication may need adjustment). 

Some forms of this medication may cause GI upset (oral medication may be taken with meals to reduce GI upset; small frequent meals and frequent mouth care may reduce GI upset). You may be more susceptible to infection (avoid crowds and persons with contagious or infective conditions).

Below is the list of medicines, which have the same composition, strength and form as Betnesol 0.5 MG Tablet , and hence can be used as its substitute.

Using your medicineEyesThe usual dose is 1 or 2 drops put into the eye up to 6 times each dayOnce the redness, itching and soreness starts to feel better, apply the drops less often.1. Tilt the head back 2. Gently pull lower eyelid downwards and outwards 3. Place drops in the gap between the lid and eye (squeeze bottle very gently if necessary) 4. Blink a few times to spread out the drops 5. Repeat for the other eye if needed.Medical checkupsIf you are using this medicine for your eyes and you use it for a number of weeks, your doctor may ask you to have check-ups. These are to make sure that your medicine is working properly and that the dose you are taking is right for you. Your doctor will check your eyes for:1. An increase in pressure 2. Cataracts 3. Infection.EarsThe usual dose is 2 or 3 drops put into the ear three or four times each dayOnce the redness, itching and soreness starts to feel better, apply the drops less often.1. 

Tilt the head to one side 2. Place drops in the ear canal (squeeze bottle gently if necessary) 3. Keep head tilted for a minute or two to let the drops soak in 4. Repeat for other ear if needed.NoseThe usual dose is 2 or 3 drops put into each nostril two or three times each day.1. Tilt head backwards 2. Place drops in nostril (squeeze bottle gently if necessary) 3. Keep head tilted and sniff gently to let the drops soak in 4.

 Repeat for other nostril if needed.Medical checkupsYour doctor will regularly check the growth of children who are taking Betnesol-N by nose over a long period of time.

Like all medicines, this medicine can cause side effects although not everybody gets them. Serious Common Uncommon Rare Very Rare suicidal thoughts feeling high (mania) or moods that go up and down feeling anxious, having problems sleeping, difficulty in thinking or being confused and losing your memory feeling, seeing or hearing things which do not exist. 

having strange and frightening thoughts

Your doctor will advise the appropriate dose that suits your infection. Betnesol N Eye/Ear Drops 5 ml is for external use only. Common side effects of Betnesol N Eye/Ear Drops 5 ml include irritation, itching, redness, burning or a stinging sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult a doctor.

Betnesol Tablet is a medication which have betamethasone.

 Commonly it is used to treat both internal and exterior inflammation (swelling and redness) brought on by ailments like severe skin allergies, arthritis, colitis, asthma, and more.

Table of Content About BetnesolPrice of Betnesol in PakistanUses of BetnesolSide Effects of BetnesolConcerns about BetnesolWhen not to use Betnesol?AllergyFungi InfectionGeneral Instructions for taking BetnesolOther DetailsDosageInteractionsWarningsSubstitutes of BetnesolMarham’s Online Services of Delivering MedicinesFAQ’sWhat is Betnesol pills used for?Is Betnesol harmful?Is Betnesol tablet is used for cough?Betnesol Tablet is a medication which have betamethasone. Commonly it is used to treat both internal and exterior inflammation (swelling and redness) brought on by ailments like severe skin allergies, arthritis, colitis, asthma, and more.And here we would see in detail about the Betnesol Tablet Uses, Side Effects and Price in Pakistan.

 So don’t go anywhere and read it calmly.About BetnesolA steroid drug is the tablet form of betnesol. It is used to reduce associated symptoms in people with allergies, immune-related illnesses, rheumatoid arthritis, bronchial asthma, skin, and other allergic conditions.

Tablets containing betnesol are useful for reducing inflammation (redness, swelling, itching). This pill contains betamethasone as the active ingredient and is a steroid medication.By attaching to the steroid receptor, it suppresses inflammation. Additionally, it promotes the skin’s organic compounds, which lowers swelling and inflammation. 

Follow the doctor’s instructions for dosage exactly.Never skip a dosage or stop taking it without first talking to your doctor. The medication must be taken for the full course. Without first consulting the doctor, do not boost the dosage or stop abruptly because doing so could make the illness state worse.Not everyone experiences the negative effects of betnesol pills, which include nausea, indigestion, and heartburn. Usually, these adverse effects vanish over time. But you should see a doctor if you believe the negative effects are still there.

Price of Betnesol in PakistanA single Betnesol tablet 4mg costs only Rs. 80-100pkr, and Betnesol Drops 7.5ml costs Rs. 50-70pkr. It is offered at pharmacies and online.By clicking here, you may use the Marham app to purchase the Betnesol tablets online.Uses of BetnesolFollowing are the uses of Betnesol tablet;An infection and an allergyWith illnesses like asthma (breathing issues)Colitis (swelling and pain in the large intestine)Lessen or prevent swelling and irritation.Swelling in the jointsTreat rheumatoid arthritis, osteoarthritis, bursitis, tendinitis, gout, and other joint-related conditions.Side Effects of BetnesolBetnesol 0.5 MG Tablet side effects are, both serious and minor:Blurred visionIncreased appetiteIndigestionHeadacheNauseaAnxiety and nervousnessSkin discolorationIrregular menstrual periodsGrowth retardation in childrenHoarseness of voiceDizzinessBloatingShortness of breathWeight gainStomach upsetConcerns about BetnesolFollowing are some concerns of people about taking Betnesol Tablet which are going to discuss in below pointers;The amount of time required for Betnesol 0.5 MG Tablet to start showing its effect is not known.The amount of time for which Betnesol 0.5 MG Tablet remains active in your body is not known.Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

No habit-forming tendencies were reported for Betnesol 0.5 MG Tablet.Betnesol 0.5 MG Tablet is not recommended for use in pregnancy as it may harm your foetus. Hence, consult your doctor before using this medicine.Betnesol 0.5 MG Tablet is not recommended for use during breastfeeding as this medicine passes into breastmilk and may harm your infant. Hence, consult an internal medicine doctor before using this medicine.When not to use Betnesol?In following conditions you should not use Betnesol tablet;

AllergyIf you have an allergy to Betnesol, stay away from taking the 0.5 MG tablet.If you experience any symptoms, including skin rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, difficulty breathing, etc.,You should seek emergency medical assistance in this case.Fungi InfectionAn infection that affects your internal organs is referred to as a systemic fungal infection.It is not advised to take Betnesol 0.5 MG Tablets if you have a fungal infection affecting one or more internal organs.Your immune system may be suppressed by this medication, worsening your disease.General Instructions for taking BetnesolSome general instructions taking into consideration while having Betnesol tablet as the treatment of your problem are;As directed by your doctor, take the Betnesol 0.5 MG Tablet.Never take more or less medication than recommended.

If you have any negative side effects while taking this medication, talk to your doctor.Without first talking to your doctor, do not discontinue taking the drug.Keep the medication out of children’s and animals’ reach.Make it useless after the expiration date.Make sure the leftover medication is properly disposed of.Other DetailsSome other important details related to Betnesol tablet is given below;DosageThe dosage recommendations for Betnesol tablet isUntaken DoseAs soon as you recall, take the Betnesol 0.5 MG Tablet that you skipped.Skip the missing dose if it is almost time for your next dose.Never take two doses at once to make up for missing ones.OverdoseIf you believe you may have taken an excessive amount of Betnesol 0.5 MG Tablet, call your doctor right away.Increased acne or facial hair, menstruation issues, skin bruises, and other side effects may result from using this medication in excess.InteractionsEach medicine has a unique interaction with each individual. Before beginning any medication, discuss with your doctor all potential interactions.

Interaction with AlcoholAlcohol and its interaction with Betnesol are unknown. It is advised to speak with your doctor before using.Interaction with MedicinesWarfarinEthinyl EstradiolAmlodipineInsulinDesmopressinCiprofloxacinDisease InteractionsInfectionsHypothyroidismHyperlipidemiaDiabetesWarningsFollowing are some warnings to know before the use of Betnesol Tablet;Withdrawal symptoms such as weakness, tiredness, weight loss, and decreased appetiteLiver diseaseVisual disturbanceKidney diseasesChicken poxMyasthenia gravisGrowth retardationSubstitutes of BetnesolFollowing is the list for the substitutes of BetnesolBetawok 0.5 MG Tablet; Wockhardt Ltd.Betnecip 0.5 MG Tablet; Cipla Ltd.Betnecort 0.5 MG Tablet; Cipla Ltd.Betni 0.5 MG Tablet; Intas Pharmaceuticals Ltd.Marham’s Online Services of Delivering MedicinesAre you thinking to go to a pharmacy for taking your medicines. but of course sometimes you may be not in a mood of going outside. Now there is no need to be worried and sad. Marham is here; order Betnesol through Marham’s online services of delivering medicines to home right now.Also you may consult Online or book an appointment with the Best Internal Medicine Specialists in Pakistan regarding any question via the Marham app today!Can’t Find the App?AndroidIOSFAQ’sWhat is Betnesol pills used for?Many different inflammatory and allergic illnesses, including as arthritis, lupus, psoriasis, ulcerative colitis, and ailments affecting the skin, blood, eyes, lungs, stomach, and nervous system, are treated with betnesol tablets.Is Betnesol harmful?The adverse effects of betnesol 0.5 MG Tablet include headache, nausea, shortness of breath, weight gain, and stomach trouble. These negative effects go away on their own. If any of these symptoms annoy you or get worse, talk to your doctor.

 If you have an allergy to this medication, avoid using it.Is Betnesol tablet is used for cough?Betnesol tablet is a steroid, not a drug. Cold and sore throat relief is not possible with it. Since viruses typically cause colds, betnesol tablets have little effect on viruses.

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ALBENDAZOLE TABLET USE

ALBENDAZOLE TABLET USE

WARNINGS Included as part of the "PRECAUTIONS" Section PRECAUTIONS Bone Marrow Suppression Fatalities associated with the use of ALBENZA have been reported due to granulocytopenia or pancytopenia. ALBENZA may cause bone marrow suppression, aplastic anemia, and agranulocytosis. 

Monitor blood counts at the beginning of each 28-day cycle of therapy, and every 2 weeks while on therapy with ALBENZA in all patients. 

Patients with liver disease and patients with hepatic echinococcosis are at increased risk for bone marrow suppression and warrant more frequent monitoring of blood counts. Discontinue ALBENZA if clinically significant decreases in blood cell counts occur. Embryo-Fetal Toxicity Based on findings from animal reproduction studies, ALBENZA may cause fetal harm when administered to a pregnant woman. Embryotoxicity and skeletal malformations were reported in rats and rabbits when treated during the period of organogenesis (at oral doses approximately 0.1 to 0.6 times the recommended human dose normalized for total body surface area). Advise pregnant women of the potential risk to a fetus. Pregnancy testing is recommended for females of reproductive potential prior to initiating ALBENZA .

 Advise females of reproductive potential to use an effective method of contraception during treatment with ALBENZA and for 3 days after the final dose . Risk Of Neurologic Symptoms In Neurocysticercosis Patients being treated for neurocysticercosis should receive steroid and anticonvulsant therapy to prevent neurological symptoms (e.g. seizures, increased intracranial pressure and focal signs) as a result of an inflammatory reaction caused by death of the parasite within the brain. Risk Of Retinal Damage In Patients With Retinal Neurocysticercosis Cysticercosis may involve the retina. Before initiating therapy for neurocysticercosis, examine the patient for the presence of retinal lesions. If such lesions are visualized, weigh the need for anticysticeral therapy against the possibility of retinal damage resulting from inflammatory damage caused by ALBENZA-induced death of the parasite. Hepatic Effects In clinical trials, treatment with ALBENZA has been associated with mild to moderate elevations of hepatic enzymes in approximately 16% of patients. These elevations have generally returned to normal upon discontinuation of therapy. There have also been case reports of acute liver failure of uncertain causality and hepatitis . Monitor liver enzymes (transaminases) before the start of each treatment cycle and at least every 2 weeks during treatment.

 If hepatic enzymes exceed twice the upper limit of normal, consideration should be given to discontinuing ALBENZA therapy based on individual patient circumstances. Restarting ALBENZA treatment in patients whose hepatic enzymes have normalized off treatment is an individual decision that should take into account the risk/benefit of further ALBENZA usage. Perform laboratory tests frequently if ALBENZA treatment is restarted. Patients with elevated liver enzyme test results are at increased risk for hepatotoxicity and bone marrow suppression . Discontinue therapy if liver enzymes are significantly increased or if clinically significant decreases in blood cell counts occur. Unmasking Of Neurocysticercosis In Hydatid Patients Undiagnosed neurocysticercosis may be uncovered in patients treated with ALBENZA for other conditions. 

Patients with epidemiologic factors who are at risk for neurocysticercosis should be evaluated prior to initiation of therapy. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Long-term carcinogenicity studies were conducted in mice and rats. No evidence of increased incidence of tumors was found in the mice or rats at up to 400 mg/kg/day or 20 mg/kg/day respectively (2 times and 0.2 times the recommended human dose on a body surface area basis).

 In genotoxicity tests, albendazole was found negative in an Ames Salmonella/Microsome Plate mutation assay, Chinese Hamster Ovary chromosomal aberration test, and in vivo mouse micronucleus test. In the in vitro BALB/3T3 cells transformation assay, albendazole produced weak activity in the presence of metabolic activation while no activity was found in the absence of metabolic activation. Albendazole did not adversely affect male or female fertility in the rat at an oral dose of 30 mg/kg/day (0.32 times the recommended human dose based on body surface area in mg/m2). Use In Specific Populations Pregnancy Risk Summary Based on findings from animal reproduction studies, ALBENZA may cause fetal harm when administered to a pregnant woman. However, available human data from a small number of published case series and reports on the use of multiple-dose albendazole in the 1st trimester of pregnancy, and several published studies on single-dose albendazole use later in pregnancy, have not identified any drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes. In animal reproductive studies, oral administration of albendazole during the period of organogenesis caused embryotoxicity and skeletal malformations in pregnant rats (at doses of 0.10 times and 0.32 times the maximum recommended human dose based on body surface area in mg/m2) and pregnant rabbits (at doses of 0.60 times the maximum recommended human dose based on body surface area in mg/m2). Albendazole was also associated with maternal toxicity in rabbits (at doses of 0.60 times the recommended human dose based on body surface area in mg/m2) (see Data). Advise a pregnant woman of the potential risk to the fetus. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. All pregnancies have a background risk of birth defects, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively. Data Animal Data Albendazole has been shown to be teratogenic (to cause embryotoxicity and skeletal malformations) in pregnant rats and rabbits. The teratogenic response in the rat was shown at oral doses of 10 and 30 mg/kg/day (0.10 times and 0.32 times the maximum recommended human dose based on body surface area in mg/m2, respectively) during organogenesis (gestation days 6 to 15) and in pregnant rabbits at oral doses of 30 mg/kg/day (0.60 times the maximum recommended human dose based on body surface area in mg/m2) administered during organogenesis (gestation days 7 to 19). In the rabbit study, maternal toxicity (33% mortality) was noted at 30 mg/kg/day. In mice, no teratogenic effects were observed at oral doses up to 30 mg/kg/day (0.16 times the recommended human dose based on body surface area in mg/m2), administered during gestation days 6 to 15. 

Lactation Risk Summary Concentrations of albendazole and the active metabolite, albendazole sulfoxide, have been reported to be low in human breast milk. There are no reports of adverse effects on the breastfed infant and no information on the effects on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for ALBENZA and any potential adverse effects on the breastfed infant from ALBENZA or from the underlying maternal condition. Females And Males Of Reproductive Potential Pregnancy Testing Pregnancy testing is recommended for females of reproductive potential prior to initiating ALBENZA. Contraception Females ALBENZA may cause fetal harm when administered to a pregnant woman . Advise females of reproductive potential to use effective contraception during treatment with ALBENZA and for 3 days after the final dose. Pediatric Use Hydatid disease is uncommon in infants and young children. In neurocysticercosis, the efficacy of ALBENZA in children appears to be similar to that in adults. Geriatric Use In patients aged 65 and older with either hydatid disease or neurocysticercosis, there was insufficient data to determine whether the safety and effectiveness of ALBENZA is different from that of younger patients. Patients With Impaired Renal Function The pharmacokinetics of ALBENZA in patients with impaired renal function has not been studied. Patients With Extra-Hepatic Obstruction In patients with evidence of extrahepatic obstruction (n = 5), the systemic availability of albendazole sulfoxide was increased, as indicated by a 2-fold increase in maximum serum concentration and a 7-fold increase in area under the curve. The rate of absorption/conversion and elimination of albendazole sulfoxide appeared to be prolonged with mean Tmax and serum elimination half-life values of 10 hours and 31.7 hours, respectively. 

Plasma concentrations of parent ALBENZA were measurable in only 1 of 5 patients.



Albendazole sulfoxide is 70% bound to plasma protein and is widely distributed throughout the body; it has been detected in urine, bile, liver, cyst wall, cyst fluid, and cerebrospinal fluid (CSF). Concentrations in plasma were 3-fold to 10-fold and 2-fold to 4-fold higher than those simultaneously determined in cyst fluid and CSF, respectively.



Albendazole binds to the colchicine‑sensitive site of β‑tubulin inhibiting their polymerization into microtubules. The decrease in microtubules in the intestinal cells of the parasites decreases their absorptive function, especially the uptake of glucose by the adult and larval forms of the parasites, and also depletes glycogen storage. Insufficient glucose results in insufficient energy for the production of adenosine trisphosphate (ATP) and the parasite eventually dies.



MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. 

Do not double the dose to catch up.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Notes Do not share this medication with others.This medication has been prescribed for your current condition only.

 Do not use it later for another infection unless your doctor tells you to.Lab and/or medical tests (such as liver function tests, complete blood counts) should be done before you start taking this medication and while you are taking it. Keep all medical and lab appointments. Consult your doctor for more details. Missed Dose If you miss a dose, take it as soon as you remember. 

If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. Storage Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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ACECLOFENAC TABLET USE

ACECLOFENAC TABLET USE

You have been prescribed Aceclofenac to relieve pain and inflammation. 

Take it with food or milk to prevent upset stomach. Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems. It may cause dizziness, drowsiness or visual disturbances. 

Use caution while driving or doing anything that requires concentration. Avoid consuming alcohol while taking Aceclofenac as it can cause excessive drowsiness and increase your risk of stomach problems. 

Inform your doctor if you have a history of heart disease or stroke. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.



Appropriate monitoring and advice are required for patients with a history of hypertension and/or mild to moderate congestive heart failure as fluid retention and oedema have been reported in association with NSAID therapy. 

Patients with congestive heart failure ( NYHA-I) and patients with significant risk factors for cardiovascular events (e.g. hypertension, hyperlipidaemia, diabetes mellitus, smoking) should only be treated with aceclofenac after careful consideration. As the cardiovascular risks of aceclofenac may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The patient's need for symptomatic relief and response to therapy should be re- evaluated periodically.



Hypersensitivity to Aceclofenac or to any of the excipients listed in section 6.1 Active, or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding). NSAIDS are contraindicated in patients who have previously shown hypersensitivity reactions (eg. Asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, aspirin, or other non-steroidal anti-inflammatory drugs. Hepatic failure and renal failure (see section 4.4). Patients with established congestive heart failure (NYHA II-IV), ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease. History of gastrointestinal bleeding or perforation, related to previous NSAIDS therapy. Active bleedings or bleeding disorders. Aceclofenac should not be prescribed during pregnancy, especially during the last trimester of pregnancy, unless there are compelling reasons for doing so. The lowest effective dosage should be used (see section 4.6).



The in vitro API release data presented a substantial improvement in dissolution rate of batch ACN-1 in comparison to marketed tablets and unprocessed aceclofenac-based tablet formulation. The graph showed that in the first 30 min, more than 85% of ACN-1 were dissolved compared to 75.89% for ACN-2, 51.06% for unprocessed micronized drug formulation (i.e. ACM-3), 59.56% for the M. Tablets and 29.41% for raw drug. Boosted in vitro release rate of ACN-1 was observed while comparing to ACN-2, unprocessed drug containing formulation i.e. ACM-3, M. Tablets and raw drug, all these results are illustrated in Figure 7. The solubility of drug compound will be enhanced when the particle size of the drug is reduced to nanosized range as described by Xia et al.33 The release data showed the P<0.001 compared with raw drug. Figure 7 In vitro dissolution of formulations and M. Tablets. Values represent mean±SD, n=3. ***P<0.001 compared with raw drug.

NSAIDs are contraindicated in patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, aspirin, or other non-steroidal anti-inflammatory drugs.

The majority of side effects observed have been reversible and of a minor nature and include gastrointestinal disorders (dyspepsia, abdominal pain, nausea), rash, ruber, urticaria, symptoms of enuresis, headache, dizziness, and drowsiness. To report suspected adverse reactions, call 1-800-FDA-1088.

The risk of GI bleeding, ulceration or perforation is higher with increasing NSAID doses, in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation (see section 4.3), and in the elderly. These patients should commence treatment on the lowest dose available. Combination therapy with protective agents (e.g. misoprostol or proton pump inhibitors) should be considered for these patients, and also for patients requiring concomitant low dose aspirin, or other drugs likely to increase gastrointestinal risk (see below and section 4.5).

Interactions with other medicinesSome medicines can affect the way aceclofenac+thiocolchicoside works or this medicine itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.Increased risk of stomach bleeding, if you take other pain killers, steroids, antidepressants along with this combination.Concomitant use of cyclosporine and tacrolimus (used in organ transplants) can lead to serious kidney damage.There is an increased risk of bleeding if aceclofenac+thiocolchicoside is taken along with other medicines like warfarin.You may experience fluctuations in blood sugar if you are taking anti-diabetic medicines like glimepiride or metformin.Do not take aceclofenac+thiocolchicoside if you have taken mifepristone lately (within 2 weeks).This combination can worsen the heart failure problem if taken with medicines for heart failure like digoxin.You may experience fits if you are taking antibiotics like ciprofloxacin, norfloxacin and ofloxacin.

a) Symptoms Symptoms include headache, nausea, vomiting, epigastric pain, gastrointestinal irritation, gastrointestinal bleeding, rarely diarrhoea, disorientation, excitation, coma, drowsiness, dizziness, tinnitus, hypotension, respiratory depression, fainting, occasionally convulsions. In cases of significant poisoning acute renal failure and liver damage are possible. b) Therapeutic measure : Patients should be treated symptomatically as required. Within one hour of ingestion of a potentially toxic amount, activated charcoal should be considered. Alternatively, in adults, gastric lavage should be considered within one hour of ingestion of a potentially life-threatening overdose. Specific therapies such as, dialysis or haemoperfusion are probable of no help in eliminating NSAIDs due to their high rate of protein binding and extensive metabolism. Good urine output should be ensured. Renal and liver function should be closely monitored. Patients should be observed for at least four hours after ingestion of potentially toxic amounts. In case of frequent or prolonged convulsions, patients should be treated with intravenous diazepam. Other measures may be indicated by the patient's clinical condition. Management of acute poisoning with oral aceclofenac essentially consists of supportive and symptomatic measuresfor complications such as hypotension, renal failure, convulsions, gastro-intestinal irritation, and respiratory depression.

Hifenac (aceclofenac) 100mg Tablet is a Tablet manufactured by Intas Pharmaceuticals Ltd. It is commonly used for the diagnosis or treatment of osteoarthritis, rheumatoid arthritis, Ankylosing spondylitis, headache, mentrual pain.

 It has some side effects such as Peptic ulcer, Abdominal pain, Nausea, Liver injury. The salts Aceclofenac are involved in the preparation of Hifenac (aceclofenac) 100mg Tablet.

This article has been medically reviewed by Dr Nikita Toshi. Isn’t it a common practice to have something special for dinner or lunch when you have a reason to celebrate? Similarly, it is not unusual for many people to skip a meal or overeat when feeling low or angry. When we are feeling down or happy, Read More

Feature Papers represent the most advanced research with significant potential for high impact in the field. Feature Papers are submitted upon individual invitation or recommendation by the scientific editors and undergo peer review prior to publication. The Feature Paper can be either an original research article, a substantial novel research study that often involves several techniques or approaches

, or a comprehensive review paper with concise and precise updates on the latest progress in the field that systematically reviews the most exciting advances in scientific literature. This type of paper provides an outlook on future directions of research or possible applications.

To investigate the mechanism of drug release from the formulated tablets, the drug release data were fitted into zero-order, first-order, Higuchi and Korsmeyer’s equation. The Korsmeyer’s equation, Equation (A), describes the drug release behaviour from the polymers.

There are no human data available on the consequences of CLANZA CR overdosage. If overdosage is observed, therapeutic measures should be taken according to symptoms; supportive and symptomatictreatment should be given for complications such as hypotension, gastro-intestinal irritation, respiratory depression, and convulsions.

Expert advice for AceclofenacYou have been prescribed Aceclofenac to relieve pain and inflammation. Take it with food or milk to prevent upset stomach. Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems. It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Avoid consuming alcohol while taking Aceclofenac as it can cause excessive drowsiness and increase your risk of stomach problems. Inform your doctor if you have a history of heart disease or stroke. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.Frequently asked questions for AceclofenacAceclofenacQ. Is Aceclofenac a good painkiller?Aceclofenac is effective in relieving pain and inflammation. It is used to provide relief from various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.Q. Is Aceclofenac safe?Aceclofenac is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.Q. Does Aceclofenac get you high?No, Aceclofenac does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.Q. Can Aceclofenac hurt your kidneys?Long-term use and high doses of Aceclofenac may cause renal problems, such as protein or blood in urine and pain during urination. Patients who had or have heart failure, impaired kidney function and hypertension are at risk of kidney problems. The risk of developing kidney problems is also high in patients who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Along with that, Aceclofenac can affect kidneys of patients who are above 65 years of age or who remain dehydrated. Therefore, kidney function monitoring is recommended for such patients.Q. What if I forget to take a dose of Aceclofenac?If you forget a dose of Aceclofenac, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.Q. Does Aceclofenac make you drowsy?Aceclofenac can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.Q. What is the most important information I need to know about Aceclofenac?It is important to know that Aceclofenac may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, the use of Aceclofenac may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.Q. Can Aceclofenac be taken during pregnancy?You should not take Aceclofenac during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Aceclofenac can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Aceclofenac during the first 6 months of pregnancy also. In some cases, Aceclofenac may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.Q. Is Aceclofenac effective?Aceclofenac is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Aceclofenac too early, the symptoms may return or worsen.

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DICLOFENAC SODIUM USE

DICLOFENAC USE

Continuing Education ActivityDiclofenac is a medication used in the management and treatment of inflammatory conditions and pain. It is in the class of non-steroidal anti-inflammatory drugs (NSAID). This activity outlines the indications, mechanism of action, administration, adverse effect profile, contraindications, and other key factors for diclofenac in the clinical setting pertinent to healthcare team members to treat and manage patients with inflammation-related conditions. Objectives: Outline the mechanisms of action of diclofenac.Review the indications for therapy with diclofenac.Summarize the potential adverse reactions of diclofenac. Outline the importance of improving care coordination among the interprofessional team to improve outcomes for patients receiving diclofenac. Access free multiple choice questions on this topic.



Voltaren and Voltarol contain the sodium salt of diclofenac. In the United Kingdom, Voltarol can be supplied with either the sodium salt or the potassium salt, while Cataflam, sold in some other countries, is the potassium salt only. However, Voltarol Emulgel contains diclofenac diethylammonium, in which a 1.16% concentration is equivalent to a 1% concentration of the sodium salt. In 2016 Voltarol was one of the biggest selling branded over-the-counter medications sold in Great Britain, with sales of £39.3 million.[52]

Kidney problems can sometimes occur with the use of NSAID medications, including diclofenac. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have pink/bloody urine or any unusual change in the amount of urine.



Important considerations for using diclofenacKeep these considerations in mind if your doctor prescribes diclofenac for you.RefillsA prescription for this medication is refillable. You shouldn’t need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.TravelWhen traveling with your medication:Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.Don’t worry about airport X-ray machines. They can’t harm your medication.You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you.Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.Clinical monitoringIf you use diclofenac for a long time, your doctor should do blood tests to check your kidney and liver function at least once a year.You should check your own blood pressure from time to time. Home blood pressure monitors are available at most pharmacies and online.Shop online for blood pressure monitors.Sun sensitivityYou may have increased sensitivity to the sun while using diclofenac. To protect your skin, use sunscreen with SPF 30 or greater.AvailabilityNot every pharmacy stocks this drug. However, you may be able to order it. When filling your prescription, be sure to call the pharmacy first to make sure they stock this drug or can order it for you.Prior authorizationMany insurance companies require a prior authorization for this form of this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.If your insurance company won’t cover this form, you may consider checking whether it will cover the tablet or capsule form instead.



Diclofenac initiators had a 50% increased rate of major adverse cardiovascular events compared with NSAID non-initiators (incidence rate ratio 1.5, 95% confidence interval 1.4 to 1.7). Supporting use of a combined endpoint, event rates consistently increased for all individual outcomes: 1.2-fold for atrial fibrillation or flutter, 1.6-fold for ischaemic stroke, 1.7-fold for heart failure, 1.9-fold for myocardial infarction, and 1.7-fold for cardiac death (fig 2 and eTable 5). Cardiac death was driven by death from heart failure (incidence rate ratio 2.3, 1.3 to 4.2), cardiac arrhythmia (1.9, 1.1 to 3.3), and myocardial infarction (1.7, 1.2 to 2.4).

Diclofenac can interact with several other medications. Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects.

Different brands of diclofenac contain different amounts of this medicine, and may have different uses. If you switch brands, your dose needs may change. Follow your doctor's instructions about how much medicine to take. Ask your pharmacist if you have any questions about the brand of diclofenac you receive at the pharmacy.Swallow the whole and do not crush, chew, or break it. tablet Take on an empty stomach, at least 1 hour before or 2 hours after a meal. ZorvolexCall your doctor if your headache does not completely go away after taking Cambia.Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.Follow all directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition.Dissolve diclofenac powder with 1 to 2 ounces of water. Do not use any other type of liquid. Stir this mixture and drink all of it right away. Diclofenac powder works best if you take it on an empty stomach. (Cambia)If you use diclofenac long-term, you may need frequent medical tests.

Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as ibuprofen, ketorolac, naproxen). These drugs are similar to diclofenac and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should keep taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

What will happen if I stop taking it? When you stop taking diclofenac tablets or capsules, or stop using the suppositories, the effects will wear off after about 15 hours.When you stop using the gel, plasters or patches, the effects will wear off after 1 or 2 days.

ContraindicationsLike other selective COX-2 inhibitors, diclofenac is contraindicated with an FDA boxed warning in patients with a history of increased cardiovascular risk such as MI or stroke. Diclofenac should not be used in bypass graft surgery of coronary artery due to a higher risk of MI and stroke. Diclofenac is also listed as a Beers list drug and should be avoided in elderly patients due to potential adverse effects involving the cardiovascular and gastrointestinal systems. It is also contraindicated in patients with a history of anaphylactoid reaction to NSAID drugs.Also, diclofenac is contraindicated in patients with mild or severe renal insufficiency due to potential negative effects of decreased renal perfusion. Clinicians should not use diclofenac or other NSAIDs in patients with a history of GI bleeds or ulcerations. Special monitoring is a consideration in patients with a history of Helicobacter pylori infection. Formulations of diclofenac with misoprostol are contraindicated in pregnant females due to possible side effects involving loss of pregnancy associated with misoprostol.

Diclofenac is a medication used in the management and treatment of inflammatory conditions and pain. It is in the class of non-steroidal anti-inflammatory drugs (NSAID). This activity outlines the indications, mechanism of action, administration, adverse effect profile, contraindications, and other key factors for diclofenac in the clinical setting pertinent to healthcare team members to treat and manage patients with inflammation-related conditions.

Patient Counseling Information This drug may cause dizziness, drowsiness or blurred vision, if affected, do not drive or operate machinery. Avoid excessive exposure of affected area to sunlight (transdermal or topical/cutaneous). Remove contact lenses prior to administration and reinsert after 15 minutes (ophthalmic).

Diclofenac Sodium 50mg with food and drinkTake this medicine with or after food.Pregnancy and breast-feeding Although not common, abnormalities have been reported in babies whose mothers have taken NSAIDs during pregnancy. You should not take DICLOFENAC SODIUM 50mg tablets during the last 3 months of pregnancy as it may affect the baby's circulation.You should advise your doctor or pharmacist if you think you might be pregnant or are up to 6 months pregnant.Taking Diclofenac Sodium 50mg tablets may make it more difficult to become pregnant. You should talk to your doctor if you are planning to become pregnant, or if you have problems getting pregnant.You should avoid taking Diclofenac Sodium whilst breast feeding.

Depending on why you're taking diclofenac, you may only need to take it for a short time. For example, if you have a sore back or toothache, you may only need to take diclofenac for 1 or 2 days.

Symptoms of overdose include lethargy, drowsiness, nausea, vomiting, and epigastric pain, and gastrointestinal bleeding.Label Hypertension, acute renal failure, respiratory depression and coma occur rarely. In case of overdose, provide supportive care and consider inducing emesis and administering activated charcoal if overdose occurred less than 4 hours prior.

See also Warning section.The enteric-coated tablet form of diclofenac is used to reduce pain, swelling (inflammation), and joint stiffness from arthritis. Reducing these symptoms helps you do more of your normal daily activities.Diclofenac is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation. This effect helps to decrease swelling, pain, or fever.Ask your doctor about non-drug treatments and/or using other medications to treat your pain.

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CLOBITA GM CREAM

Clobita gm

Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.

In wet places such as changing rooms and gym showers, don't walk on barefoot. Wear flip-flops or sandals to prevent fungal infections.Do not scratch the affected area of skin as it can spread the infection to other body parts.Avoid sharing towels, combs, bedsheets, shoes or socks with others to prevent the spread of infection.Wash your bed sheets and towels regularly.Eat foods rich in quercetin, such as apples, 

cherry, broccoli, spinach and blueberries.Consuming food rich in probiotics helps in developing the immune system against allergies.Limit foods like dairy products, soy, eggs, and nuts that might trigger allergies.Avoid the consumption of foods with excess sugar as it may flare up inflammation.Include fruits, vegetables, whole grains, healthy fats and fish in your diet.Avoid getting in contact with harsh soaps, detergents and rough fabrics.



Clobeta GM Cream 10 gm is a combination of Borax, Clobetasol, Miconazole, and Neomycin. Clobetasol is a corticosteroid that inhibits the release of certain chemical messengers in the body that cause redness,

 itching and swelling. Miconazole is an antifungal that works by causing holes in the fungal cell membranes and kills fungi. Neomycin is an antibiotic that inhibits the production of essential proteins that are necessary for bacteria to grow,

 multiply and increase in numbers. Borax is an additive mineral that provides necessary nutrients, removes dead skin cells and prevents microbial infections. Thereby, together it kills the microbes and keeps your skin free from microbial infections.



The festive season is around the corner and we are gearing up to celebrate with our near and dear ones. Along with celebrations, most festive periods come with unhealthy binge eating, leading to fitness regimes going for a toss and several health issues settling in. So the million-dollar question is; How do you eat healthy

A: No, it should not be used for burns. You should not apply this cream on the skin surface which has cuts, wounds or burns.



Diet & Lifestyle AdviseRegularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.In wet places such as changing rooms and gym showers, don't walk on barefoot. Wear flip-flops or sandals to prevent fungal infections.Do not scratch the affected area of skin as it can spread the infection to other body parts

.Avoid sharing towels, combs, bedsheets, shoes or socks with others to prevent the spread of infection.Wash your bed sheets and towels regularly.Eat foods rich in quercetin, such as apples, cherry, broccoli, spinach and blueberries.Consuming food rich in probiotics helps in developing the immune system against allergies.

Limit foods like dairy products, soy, eggs, and nuts that might trigger allergies.Avoid the consumption of foods with excess sugar as it may flare up inflammation.Include fruits, vegetables, whole grains, healthy fats and fish in your diet.Avoid getting in contact with harsh soaps, detergents and rough fabrics.

Medicinal BenefitsClobeta GM Cream 10 gm is a combination of Borax, Clobetasol, Miconazole, and Neomycin. Clobetasol is a corticosteroid that inhibits the release of certain chemical messengers in the body that cause redness, itching and swelling. Miconazole is an antifungal that works by causing holes in the fungal cell membranes and kills fungi. Neomycin is an antibiotic that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply and increase in numbers. Borax is an additive mineral that provides necessary nutrients, removes dead skin cells and prevents microbial infections.

 Thereby, together it kills the microbes and keeps your skin free from microbial infections.

Clobeta GM Cream 10 gm is a combination of Clobetasol (corticosteroid), Miconazole (antifungal), Neomycin (antibiotic), and Borax (an additive that removes dead skin and microbes). Clobetasol blocks the production of prostaglandins (chemical messengers), making the skin red, swollen and itchy. Miconazole is an antifungal agent that works by causing holes in the fungal cell membranes and kills fungi. Neomycin is an antibiotic used in treating bacterial and fungal infections of the skin. 

It prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Borax is a mineral that provides necessary nutrients to the body.

I am using this clobeta gm for ring worm at this .where it seems to be like curing, the red colour has being healing. Dr.Jyoti Biswas MBBS,MD(medicine) General Physician, Kolkata Clobetasol alone is not enough. You need 2 oral medicine and 2 creams for 1 month .then it will be curable need details evaluation and treatment you can chat with me clicking on" text consultation" option if you wish thanks.

A: Both Clobeta GM and Lobate GM are topical antimicrobial and steroid medicines that are used for the treatment of various skin conditions. However, they differ in their composition. Clobeta GM cream contains a combination of clobetasol, zinc, borax, neomycin, and miconazole as the active substances while Lobate GM cream contains clobetasol, neomycin, 

and miconazole as active substances. You should always use the medicine that is prescribed to you by your doctor.

Clobeta GM Cream 10 gm belongs to a class of dermatological medication that is used to reduce swelling, itching and redness caused due to bacterial and fungal skin infections. Fungal infection is a skin disease in which a fungus attacks the tissue and causes an infection. Bacterial skin infection occurs when bacteria penetrate through hair follicles or the skin breaks and infects the skin.Clobeta GM Cream 10 gm is a combination of Clobetasol (corticosteroid), Miconazole (antifungal), Neomycin (antibiotic), and Borax (an additive that removes dead skin and microbes). Clobetasol blocks the production of prostaglandins (chemical messengers), making the skin red, swollen and itchy. Miconazole is an antifungal agent that works by causing holes in the fungal cell membranes and kills fungi. Neomycin is an antibiotic used in treating bacterial and fungal infections of the skin. It prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Borax is a mineral that provides necessary nutrients to the body.Clobeta GM Cream 10 gm is for external use only. 

It is generally safe to use. Some may experience side effects like dry skin, burning, irritation, itching, and redness at the application site. Most of these side effects of Clobeta GM Cream 10 gm do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.Brief your medical history to the doctor, if you are allergic to Clobeta GM Cream 10 gm or any of its components. Let your doctor know if have any fungal infections or any viral infections, 

acne, rosacea, and psoriasis. Pregnant and breastfeeding women should use Clobeta GM Cream 10 gm with proper consultation and caution. Do not wrap or cover the treated area with bandages unless advised by your doctor. Do not apply Clobeta GM Cream 10 gm to broken skin or cuts

. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. If you have adrenal gland or liver problems, inform your doctor before taking Clobeta GM Cream 10 gm.

I am suffering from ringworm from 15 days, and I have used lobate gm cream and terbinaforce plus also but no result now am using clobeta gm cream, clobeta gm treat ringworm? Which cream I have to use for finish ringworm? Clobeta gm treat ringworm? Dr.Rejath Raj MD - Dermatology, Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.), Medicine Dermatologist, Bangalore Good afternoon. Clobate gm worsens ringworm. Kindly consult a qualified dermatologist either in person or via online consultation for proper treatment of your condition. Avoid self medicating for your own good.

A: Burning, irritation, itching, thinning of skin are a few common side effects that can be observed during the treatment with this cream. However, these symptoms are usually mild and resolve on your own. Also, it is not important that everyone experience the same.

The festive season is around the corner and we are gearing up to celebrate with our near and dear ones. Along with celebrations, most festive periods come with unhealthy binge eating, leading to fitness regimes going for a toss and several health issues settling in. So the million-dollar question is; How do you eat healthy Read More

Avoid These Foods If You Have Anxiety Or Depression!This article has been medically reviewed by Dr Nikita Toshi. Isn’t it a common practice to have something special for dinner or lunch when you have a reason to celebrate? Similarly, it is not unusual for many people to skip a meal or overeat when feeling low or angry. When we are feeling down or happy, Read More

About Clobeta GM Cream 10 gmClobeta GM Cream 10 gm belongs to a class of dermatological medication that is used to reduce swelling, itching and redness caused due to bacterial and fungal skin infections. Fungal infection is a skin disease in which a fungus attacks the tissue and causes an infection. Bacterial skin infection occurs when bacteria penetrate through hair follicles or the skin breaks and infects the skin.

Clobeta GM Cream 10 gm is a combination of Clobetasol (corticosteroid), Miconazole (antifungal), Neomycin (antibiotic), and Borax (an additive that removes dead skin and microbes). Clobetasol blocks the production of prostaglandins (chemical messengers), making the skin red, swollen and itchy. Miconazole is an antifungal agent that works by causing holes in the fungal cell membranes and kills fungi. Neomycin is an antibiotic used in treating bacterial and fungal infections of the skin. It prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Borax is a mineral that provides necessary nutrients to the body.Clobeta GM Cream 10 gm is for external use only. It is generally safe to use. Some may experience side effects like dry skin, 

burning, irritation, itching, and redness at the application site. Most of these side effects of Clobeta GM Cream 10 gm do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.Brief your medical history to the doctor, if you are allergic to Clobeta GM Cream 10 gm or any of its components. 

Let your doctor know if have any fungal infections or any viral infections, acne, rosacea, and psoriasis. Pregnant and breastfeeding women should use Clobeta GM Cream 10 gm with proper consultation and caution. 

Do not wrap or cover the treated area with bandages unless advised by your doctor. Do not apply Clobeta GM Cream 10 gm to broken skin or cuts. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately.

 If you have adrenal gland or liver problems, inform your doctor before taking Clobeta GM Cream 10 gm.

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SURFAZ AN CREAM USE

SURFAZ SN CREAM

Disease/Condition GlossaryThe swelling of the skin occurs when an allergic reaction or skin irritation releases several substances in the skin that widens blood vessels and cause itching, redness, pain, and swelling in the irritated area. Psoriasis is a skin condition in which skin cells multiply faster than normal, resulting in white scales and itchy, dry patches. Dermatitis is a common skin condition associated with dry, itchy, or swollen skin. Eczema is a skin condition that causes itchy, cracked, swollen, or rough skin.



Surfaz SN Cream 10 gm belongs to a class of topical corticosteroid medications used to treat skin conditions such as psoriasis, eczema and dermatitis. Surfaz SN Cream 10 gm contains Beclomethasone dipropionate, a corticosteroid having anti-inflammatory properties. It reduces swelling, redness, and itching by inhibiting the production of certain chemical messengers in the body that cause inflammation. Thus, Surfaz SN Cream 10 gm aids in treating skin conditions such as Psoriasis, Eczema and Dermatitis.



Are there any missed dose instructions? Contact your doctor for instructions if you missed a scheduled dose of this medication. A self-attempt to make up for the lost dose may result in adverse effects. Are there any overdose instructions? Contact your doctor if an overdose with this medication for is suspected especially when the prescribed dose is very high. Symptoms may include thinning of the skin, easy bruising and bleeding, body fat deposits etc.



Ans: Major and minor side effects of Surfaz-Sn Cream are itching, allergic contact dermatitis, acneiform eruptions, erythema, edema, and burning. Apart from these, it may also lead to conditions such as irritation, dryness, folliculitis, hypertrichosis, hypopigmentation, perioral dermatitis, maceration of the skin, secondary infections. These are rarely observed and the patient should contact a doctor immediately if any of these symptoms are experienced on a regular basis. These are reported in a small fraction of the population.

Surfaz SN Cream 10gm Information Surfaz SN Cream 10gm is a prescription medicine that is available as a Cream. Secondary and off-label uses of Surfaz SN Cream 10gm have also been mentioned below.The correct dosage of Surfaz SN Cream 10gm depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.Surfaz SN Cream 10gm also has some side effects, the most common being Skin Rash. While these are the most often observed Surfaz SN Cream 10gm side effects, there are can be others also. These have been listed below. These side effects of Surfaz SN Cream 10gm are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away. Surfaz SN Cream 10gm's effect during pregnancy is Severe and Moderate while nursing. In addition, Surfaz SN Cream 10gm's effects on the liver, heart and kidney are discussed below in the Surfaz SN Cream 10gm related warnings section.Surfaz SN Cream 10gm can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Surfaz SN Cream 10gm in conditions like Liver Disease, Scleroderma, Tuberculosis (TB). Some other conditions that can be affected by Surfaz SN Cream 10gm are listed in the contraindications section below.Additionally, Surfaz SN Cream 10gm may also adversely react with other medicines. See below for a complete list. In addition to the above precautions for Surfaz SN Cream 10gm, it is important to know that it is not safe while driving, and is not habit-forming.

Is it safe to use the cream in all stages of pregnancy? Although pregnant women have nothing to fear, if you are pregnant or you are planning to conceive, your doctor has to prescribe you the medication after learning about your condition. If he recommends, then the cream is safe for use.

Safety Precaution Use exactly as directed on the label, or as prescribed by your doctor. Inform your physician about all your medical conditions, any allergies, and any other topical medicines you use.

Safety AdviceAlcoholIt is not known if alcohol interacts with Surfaz SN Cream 10 gm. However, as a precautionary measure, limit or avoid the consumption of alcohol.PregnancySurfaz SN Cream 10 gm should only be used if your dermatologist or skin specialist has prescribed it and supervises your therapy.Breast FeedingPlease consult the doctor. It is given to nursing mothers only if the doctor thinks the benefits outweigh the risks. If you're using Surfaz SN Cream 10 gm on your breasts, wash off Surfaz SN Cream 10 gm from your breasts before feeding your baby.DrivingSurfaz SN Cream 10 gm does impact your ability to drive or operate machinery.LiverPlease consult your doctor if you have liver problems.KidneyPlease consult your doctor if you have kidney problems.

How many times should I apply the cream in a day? Ideally, applying a thin layer of the cream in the clean, affected area is recommended. However, your physician?s recommendation should be your holy grail.

This article has been medically reviewed by Dr Nikita Toshi. Isn’t it a common practice to have something special for dinner or lunch when you have a reason to celebrate? Similarly, it is not unusual for many people to skip a meal or overeat when feeling low or angry. When we are feeling down or happy,

A: Yes, Surfraz SN can be used for ringworm, a fungal infection. It contains clotrimazole which is effective in treating fungal infection. Surfraz SN ointment provides relief from various infections such as bacterial, fungal, or mixed. It kills and prevents the growth of the infection, thus providing relief from the symptoms of infection.

The festive season is around the corner and we are gearing up to celebrate with our near and dear ones. Along with celebrations, most festive periods come with unhealthy binge eating, leading to fitness regimes going for a toss and several health issues settling in. So the million-dollar question is; How do you eat healthy

About Surfaz-Sn Cream Surfaz-Sn Cream is primarily for the topical treatment of various dermal fungal infections. It is a combination of medicament containing Betamethasone, Clotrimazole, and Neomycin. It is helpful in treating many skin diseases including psoriasis and dermatitis and various others as well. This medicament also alleviates inflammatory symptoms including swelling, itching and redness. It is for external use only; do not use on open wounds. usually, it is applied twice daily, but you need to follow the doctors prescription for its dosage. Before applying, the patient must clean the skin and dry it. Also, he must wash and dry his hands before applying the medicament. You must rinse with water if its get into your eyes, mouth, nose or vagina. It may take a few days and even weeks for the symptoms of the disease to get improved. You must complete the course of treatment to ensure complete and better medicaments efficacy. One must inform their doctor if the condition does not improves or get worse. Before taking Surfaz-Sn Cream, you must inform your doctor if you are taking any other medicine for treating the same or any other disease, or pregnant/breastfeeding. The patient must refrain the use of this medicament if he/she is allergic to it and consult the doctor for alternative treatment for it. Also Read: Phlogam Tablet Uses and Side Effects

Betamethasone dipropionate is a highly potent corticosteroid prescription drug that can be used topically (applied to the skin) to treat inflammatory skin conditions. It should be used only under the supervision of a health care professional. Side effects from topical use include skin irritation and, with prolonged use, skin weakening or deterioration. Topical corticosteroids can be absorbed in sufficient amounts to produce adverse effects, including symptoms of adrenal suppression (low blood pressure, low blood sugar, weight loss, muscle pain, gastrointestinal problems, and severe fatigue) or Cushing’s syndrome (high blood pressure, high blood sugar, weight gain, muscle weakness, bone loss, and severe fatigue) depending on how much has been absorbed. Betamethasone dipropionate should not be used by pregnant or nursing women.

If I have kidney or liver ailments, can I use the cream? The surfaz sn cream has been rendered safe for those who suffer from kidney or liver ailments and there are no reports of any problems. However, do inform your doctor if your dosage shall be affected because of your ailments.

The correct dosage of Surfaz SN Cream 10gm depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

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